Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.36 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19512084 | 0.81 | LPAR3 (0.60) | CYP3A4TSHRLPAR3LPAR2LPAR1 | |
| SCHEMBL8976946 | 0.81 | LPAR3 (0.59) | CYP3A4TSHRLPAR3LPAR2LPAR1 | |
| SCHEMBL665394 | 0.81 | LPAR3 (0.59) | CYP3A4TSHRLPAR3LPAR2LPAR1 | |
| SCHEMBL30106183 | 0.81 | LPAR3 (0.59) | CYP3A4TSHRLPAR3LPAR2LPAR1 | |
| SCHEMBL9437010 | 0.81 | LPAR3 (0.59) | CYP3A4TSHRLPAR3LPAR2LPAR1 | |
| SCHEMBL5701887 | 0.81 | LPAR3 (0.59) | CYP3A4TSHRLPAR3LPAR2LPAR1 | |
| SCHEMBL2521046 | 0.81 | LPAR3 (0.59) | CYP3A4TSHRLPAR3LPAR2LPAR1 | |
| SCHEMBL18309262 | 0.81 | LPAR3 (0.59) | CYP3A4TSHRLPAR3LPAR2LPAR1 | |
| SCHEMBL19077685 | 0.81 | LPAR3 (0.59) | CYP3A4TSHRLPAR3LPAR2LPAR1 | |
| SCHEMBL2523265 | 0.81 | LPAR3 (0.59) | CYP3A4TSHRLPAR3LPAR2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030543-A | A TRIALKOXYALKYL PHOSPHATE ESTER, A TRIALKYL PHOSPHATE OR A MIXTURE THEREOF, AND A TRIALKYL PHOSPHITE ESTER HAVING A POUR POINT OF LESS THAN-50.DEGREE. C.; EXTREME TEMPERATURE LUBRICANTS; WEAR, CORROSION AND HEAT RESISTANCES; RHEOLOGY | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |