Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | PYGB | P11216 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051986 | 0.84 | AKR1B1 (0.49) | AKR1B1CA1CA2CA9PYGB | |
| SCHEMBL9616492 | 0.83 | CA1 (0.50) | AKR1B1CA1CA2CA9PYGB | |
| SCHEMBL6934741 | 0.83 | CA1 (0.50) | AKR1B1CA1CA2CA9PYGB | |
| SCHEMBL3810831 | 0.83 | CA1 (0.50) | AKR1B1CA1CA2CA9PYGB | |
| SCHEMBL5189446 | 0.83 | AKR1B1 (0.53) | AKR1B1CA1CA2CA9PYGB | |
| SCHEMBL7253811 | 0.83 | CA1 (0.50) | AKR1B1CA1CA2CA9PYGB | |
| SCHEMBL18642492 | 0.83 | CA1 (0.50) | AKR1B1CA1CA2CA9PYGB | |
| SCHEMBL8041486 | 0.82 | AKR1B1 (0.49) | AKR1B1CA1CA2CA9PYGB | |
| SCHEMBL7893924 | 0.80 | CA1 (0.47) | AKR1B1CA1CA2CA9PYGB | |
| SCHEMBL6538422 | 0.79 | AKR1B1 (0.46) | AKR1B1CA1CA2CA9PYGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999045016-A9 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | METABASIS THERAPEUTICS INC (US) | 2000-03-02 | — | — | WO | disclosed |