SCHEMBL8052178

SCHEMBL8052178

CCC1(N)C=CC=CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28180883 0.78
SCHEMBL3340980 0.76
SCHEMBL28223994 0.76
SCHEMBL6078053 0.71
SCHEMBL2053299 0.70 GAA (0.30)
SCHEMBL4593285 0.70
SCHEMBL4140175 0.70
SCHEMBL6774149 0.69
Hydrochloric Acid SCHEMBL29077454 0.68
SCHEMBL17420135 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117479964-A Tissue-selective single-component mRNA delivery vector and delivery system 中国科学院过程工程研究所 2024-01-30 CN disclosed
WO-2022032144-A1 SUBSTRATE ADAPTOR INHIBITORS OF PRMT5 AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2022-02-10 WO disclosed
EP-0785924-B1 BIS-2-AMINOPYRIDINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR CONTROLLING PARASITIC INFECTIONS VIRBAC SA (FR) 2000-05-03 EP disclosed
US-5834491-A CONTROLLING PARASITIC INFECTIONS WITHIN RED BLOOD CELLS; MALARIA, BABESIASIS VIRBAC (FR) 1998-11-10 US disclosed
EP-0785924-A1 BIS-2-AMINOPYRIDINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR CONTROLLING PARASITIC INFECTIONS VIRBAC S.A. (FR) 1997-07-30 EP disclosed
WO-1996011910-A1 BIS-2-AMINOPYRIDINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR CONTROLLING PARASITIC INFECTIONS VIRBAC (FR) 1996-04-25 WO disclosed