SCHEMBL8052471

SCHEMBL8052471

CCC1(C)CC1.Cl[SiH](Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5756962 0.87
SCHEMBL613348 0.87
Ammonia Solution, Strong SCHEMBL354382 0.83
SCHEMBL8050124 0.83
Hydrogen Sulfide SCHEMBL5678752 0.83
SCHEMBL23655465 0.78 KDM4E (0.36) KDM4ELMNACYP2C19
SCHEMBL2289717 0.73
SCHEMBL597791 0.73
SCHEMBL22641360 0.73 KDM4E (0.33) KDM4ELMNACYP2C19
SCHEMBL16119813 0.73 KDM4E (0.33) KDM4ELMNACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6046350-A Tertiary alkylsilane NIPPON OIL CO., LTD. (JP) 2000-04-04 US disclosed
EP-0922706-A2 Tertiary alkylsilane NIPPON OIL CO. LTD. (JP) 1999-06-16 EP disclosed