SCHEMBL8052827

SCHEMBL8052827

CS(=O)(=O)N1Cc2cc(Br)ccc2N(C(=O)Cc2c[nH]cn2)C(I)C1Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 17/20 0.45
FNTB P49356 17/20 0.45
MMP2 P08253 1/20 0.31
BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3500011 0.83 FNTA (0.56) FNTAFNTB
SCHEMBL3500006 0.83 FNTA (0.56) FNTAFNTB
SCHEMBL3501898 0.76 FNTA (0.71) FNTAFNTB
SCHEMBL3500319 0.76 FNTA (0.71) FNTAFNTB
SCHEMBL3500321 0.76 FNTA (0.71) FNTAFNTB
SCHEMBL3500027 0.75 FNTA (0.65) FNTAFNTB
SCHEMBL3502310 0.75 FNTA (0.50) FNTAFNTBMMP2
SCHEMBL3500024 0.75 FNTA (0.65) FNTAFNTB
SCHEMBL3499855 0.71 FNTA (0.71) FNTAFNTB
SCHEMBL3499828 0.70 FNTA (0.63) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6011029-A BENZODIAZEPINE COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2000-01-04 US disclosed