⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805273 | 1.00 | — | — | |
| SCHEMBL15116731 | 1.00 | — | — | |
| SCHEMBL12046586 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL12046596 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL2750798 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL12046589 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL12046587 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL13038040 | 0.79 | TSHR (0.35) | — | |
| SCHEMBL16590730 | 0.79 | TSHR (0.35) | — | |
| SCHEMBL16590731 | 0.79 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240244978-A1 | POLYMER PIEZOELECTRIC FILM ELEMENT, POWER STORAGE DEVICE USING SAME, AND LOAD DETECTION DEVICE | MITSUI CHEMICALS, INC. (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20230383050-A1 | DYNAMIC BONDS FOR DOUBLE DEGRADATION FEATURES IN POLYMERIC MATERIALS | SAUDI ARABIAN OIL COMPANY (SA) | 2023-11-30 | — | — | US | disclosed |
| US-20230176495-A1 | PIGMENT DISPERSION AND TONER | CANON KABUSHIKI KAISHA (JP) | 2023-06-08 | — | — | US | disclosed |
| US-20180155747-A1 | Lactate Production Process | NATUREWORKS LLC (US) | 2018-06-07 | — | — | US | disclosed |
| US-20170298097-A1 | Peptide Derivatives and Uses Thereof | NOSOPHARM (FR) | 2017-10-19 | — | — | US | disclosed |
| US-9783577-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-10-10 | — | — | US | disclosed |
| EP-2379619-B2 | ISOTACTIC POLYLACTIC ACID AND METHOD FOR PRODUCING SAME | FUTERRO SA (BE) | 2017-01-04 | — | — | EP | disclosed |
| US-20160115203-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-04-28 | — | — | US | disclosed |
| EP-2220061-B1 | SPIRO-CONDENSED 1, 3, 4-THIADIAZOLE DERIVATIVES FOR INHIBITING KSP KINESIN ACTIVITY | MERCK SHARP & DOHME (US) | 2016-02-17 | — | — | EP | disclosed |
| US-9250237-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-02-02 | — | — | US | disclosed |
| US-20120070370-A1 | SPIRO 1,3,4-THIADIAZOLINE DERIVATIVES AS KSP INHIBITORS | MERCK SHARP & DOHME CORP. | 2012-03-22 | — | — | US | disclosed |
| US-20110171172-A1 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | MERCK SHARP & DOHME CORP. | 2011-07-14 | — | — | US | disclosed |
| US-20110123435-A1 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | MERCK SHARP & DOHME LLC | 2011-05-26 | — | — | US | disclosed |
| WO-2010131022-A1 | [1,2,4] TRIAZOLO [4,3-B] PYRIDAZINES AS LIGANDS OF THE ANDROGEN RECEPTOR | ASTRAZENECA AB (SE) | 2010-11-18 | — | — | WO | disclosed |
| US-20100292222-A1 | CHEMICAL COMPOUNDS 751 | ASTRAZENECA AB (SE) | 2010-11-18 | — | — | US | disclosed |
| US-20100292222-A1 | CHEMICAL COMPOUNDS 751 | ASTRAZENECA AB (SE) | 2010-11-18 | — | — | US | disclosed |
| WO-2010132520-A1 | SPIRO 1,3,4-THIADIAZOLINE DERIVATIVES AS KSP INHIBITORS | SCHERING CORPORATION (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2009061596-A1 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | SCHERING CORPORATION (US) | 2009-05-14 | — | — | WO | disclosed |
| WO-2009061595-A1 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | SCHERING CORPORATION (US) | 2009-05-14 | — | — | WO | disclosed |
| WO-2009052288-A1 | SPIRO-CONDENSED 1, 3, 4-THIADIAZOLE DERIVATIVES FOR INHIBITING KSP KINESIN ACTIVITY | SCHERING CORPORATION (US) | 2009-04-23 | — | — | WO | disclosed |