SCHEMBL8053473

SCHEMBL8053473

Oc1c(Cc2ccc(Cl)cc2Cl)cc(Cl)cc1Cc1ccc(Cl)cc1Cl

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.69
CYP2C19 P33261 3/20 0.69
HIF1A Q16665 2/20 0.69
HSP90AA1 P07900 2/20 0.58
CYP3A4 P08684 5/20 0.55
IDO1 P14902 4/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
MEN1 O00255 2/20 0.55
USP2 O75604 2/20 0.55
MAPT P10636 2/20 0.55
CASP1 P29466 2/20 0.55
KMT2A Q03164 2/20 0.55
HPGD P15428 2/20 0.55
HTT P42858 2/20 0.55
SLC22A1 O15245 1/20 0.55
LMNA P02545 1/20 0.55
HSPD1 P10809 1/20 0.55
HSPA5 P11021 1/20 0.55
ALOX15 P16050 1/20 0.55
ALOX12 P18054 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2097653 0.85 IDO1 (0.65) CYP2C9CYP2C19HIF1AHSP90AA1CYP3A4
SCHEMBL29511471 0.82 HIF1A (1.00) CYP2C9CYP2C19HIF1AHSP90AA1CYP3A4
SCHEMBL15459932 0.82 HIF1A (1.00) CYP2C9CYP2C19HIF1AHSP90AA1CYP3A4
SCHEMBL11248603 0.82 MAPT (0.57) CYP2C9CYP2C19HIF1AHSP90AA1CYP3A4
SCHEMBL15459933 0.82 HIF1A (1.00) CYP2C9CYP2C19HIF1AHSP90AA1CYP3A4
SCHEMBL6115713 0.82 HIF1A (1.00) CYP2C9CYP2C19HIF1AHSP90AA1CYP3A4
SCHEMBL15459929 0.82 HIF1A (1.00) CYP2C9CYP2C19HIF1AHSP90AA1CYP3A4
SCHEMBL67608 0.81 HSP90AA1 (0.74) CYP2C9CYP2C19HIF1AHSP90AA1CYP3A4
Dichlorophen SCHEMBL18694833 0.76 CYP3A4 (0.71) CYP2C9CYP2C19HIF1AHSP90AA1CYP3A4
SCHEMBL6118476 0.74 MEN1 (0.62) CYP2C9CYP2C19HIF1AHSP90AA1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5371153-A Dipping aromatic polyamide fibers for rubber reinforcement in dispersion of aromatic epoxide and aromatic amine, drying, curing, dipping in solution containing resorcinol-formaldehyde resin, rubber latex, substituted phenol, drying, curing SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1994-12-06 US claimed
US-20150167232-A1 POLYESTER FIBER CORD FOR REINFORCING RUBBER TORAY INDUSTRIES, INC. (JP) 2015-06-18 US disclosed
EP-0649921-B1 HIGH-STRENGTH POLYAMIDE FIBER TORAY INDUSTRIES (JP) 2000-05-17 EP disclosed
US-5514471-A HIGH TENACITY, ELONGATION, TOUGHNESS TORAY INDUSTRIES, INC. (JP) 1996-05-07 US disclosed
EP-0506975-B1 PROCESS FOR PRODUCING AROMATIC POLYAMIDE FIBER FOR RUBBER REINFORCEMENT SUMITOMO CHEMICAL CO (JP) 1996-01-03 EP disclosed
EP-0649921-A1 HIGH-STRENGTH POLYAMIDE FIBER TORAY INDUSTRIES, INC. (JP) 1995-04-26 EP disclosed
US-5371153-A Dipping aromatic polyamide fibers for rubber reinforcement in dispersion of aromatic epoxide and aromatic amine, drying, curing, dipping in solution containing resorcinol-formaldehyde resin, rubber latex, substituted phenol, drying, curing SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1994-12-06 US disclosed
EP-0506975-A1 PROCESS FOR PRODUCING AROMATIC POLYAMIDE FIBER FOR RUBBER REINFORCEMENT SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1992-10-07 EP disclosed