Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.73 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.73 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.73 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197730 | 1.00 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DCTSK | |
| SCHEMBL8053495 | 1.00 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DCTSK | |
| SCHEMBL7865657 | 0.92 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6812699 | 0.92 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7863423 | 0.92 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6546049 | 0.90 | PDE4B (0.82) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6546052 | 0.90 | PDE4B (0.82) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6546406 | 0.90 | PDE4B (0.82) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8054590 | 0.90 | PDE4A (0.84) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8054589 | 0.90 | PDE4A (0.84) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6118017-A | Substituted-(3-cyclopentyloxy-4-methoxyphenyl)-3-phenylcyanocyclobutan-1-one | SMITHKLINE BEECHAM CORPORATION (US) | 2000-09-12 | — | — | US | disclosed |