Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902604 | 0.99 | SLC1A3 (0.49) | CETPCSNK1ESLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3319284 | 0.94 | SLC1A3 (0.50) | CETPSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL6659171 | 0.94 | SLC1A3 (0.50) | CETPSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL6659175 | 0.94 | SLC1A3 (0.50) | CETPSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL2088824 | 0.85 | CETP (0.49) | CETPCSNK1EMEN1KMT2ACTRC | |
| SCHEMBL8898336 | 0.85 | CETP (0.49) | CETPCSNK1EMEN1KMT2ACTRC | |
| SCHEMBL2089840 | 0.85 | CETP (0.49) | CETPCSNK1EMEN1KMT2ACTRC | |
| SCHEMBL2087815 | 0.85 | CETP (0.49) | CETPCSNK1EMEN1KMT2ACTRC | |
| SCHEMBL2088389 | 0.85 | CETP (0.49) | CETPCSNK1EMEN1KMT2ACTRC | |
| SCHEMBL8899236 | 0.85 | CETP (0.49) | CETPCSNK1EMEN1KMT2ACTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028110-A | Succinyl hydroxamic acid, N-formyl-N-hydroxy amino carboxylic acid and succinic acid amide derivatives as metalloprotease inhibitors | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2000-02-22 | — | — | US | disclosed |
| EP-0763012-B1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-06-09 | — | — | EP | disclosed |
| EP-0763012-A1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032944-A1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-12-07 | — | — | WO | disclosed |