Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055896 | 1.00 | MIF (0.53) | MIFALDH1A1CA1CA2CA4 | |
| SCHEMBL28791758 | 0.87 | MIF (0.54) | MIFALDH1A1CA1CA2CA4 | |
| SCHEMBL1389241 | 0.86 | MIF (0.41) | MIFALDH1A1CA1CA2CA4 | |
| SCHEMBL585287 | 0.86 | MIF (0.53) | MIFALDH1A1CA1CA2CA4 | |
| SCHEMBL585286 | 0.86 | MIF (0.53) | MIFALDH1A1CA1CA2CA4 | |
| SCHEMBL1285273 | 0.83 | MIF (0.58) | MIFALDH1A1CA1CA2CA4 | |
| SCHEMBL29462469 | 0.83 | MIF (0.58) | MIFALDH1A1CA1CA2CA4 | |
| SCHEMBL1285274 | 0.83 | MIF (0.58) | MIFALDH1A1CA1CA2CA4 | |
| SCHEMBL18797918 | 0.82 | CA1 (0.52) | MIFALDH1A1CA1CA2CA4 | |
| SCHEMBL2438320 | 0.80 | KDM4E (0.50) | MIFALDH1A1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063818-A | Substituted benzylidene indenyl formamides, acetamides and propionamides | CELL PATHWAYS INC. (US) | 2000-05-16 | — | — | US | disclosed |