Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14038141 | 0.89 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4400182 | 0.84 | KMT2A (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4195770 | 0.84 | MEN1 (0.70) | MAOBKMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL7594600 | 0.81 | MRGPRX4 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1664013 | 0.81 | CA12 (0.75) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19809534 | 0.81 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6840895 | 0.81 | MRGPRX4 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5415007 | 0.79 | CA12 (0.73) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3176831 | 0.79 | CYP2C9 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20644671 | 0.79 | CA12 (0.41) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785920-B1 | MULTIFUNCTIONAL CROSS-LINKING REAGENTS FOR HEMOGLOBIN, AND CROSS-LINKED HEMOGLOBIN CONJUGATES | KLUGER RONALD (CA) | 2000-05-17 | — | — | EP | disclosed |
| US-5811521-A | Multifunctional crosslinking reagents for hemoglobin, and crosslinked hemoglobin conjugates | KLUGER RONALD H (CA) | 1998-09-22 | — | — | US | disclosed |