Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 15/20 | 0.74 |
| ▸ | MME | P08473 | 9/20 | 0.74 |
| ▸ | CCKBR | P32239 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359930 | 0.88 | ACE (0.59) | ACEMMECCKBR | |
| SCHEMBL10908180 | 0.87 | ACE (0.76) | ACEMMECCKBR | |
| SCHEMBL10908178 | 0.87 | ACE (0.76) | ACEMMECCKBR | |
| SCHEMBL27662942 | 0.86 | ACE (0.68) | ACEMMECCKBR | |
| SCHEMBL8050289 | 0.86 | ACE (0.70) | ACEMMECCKBR | |
| SCHEMBL11050154 | 0.84 | ACE (0.66) | ACEMMECCKBR | |
| SCHEMBL8673708 | 0.84 | ACE (0.66) | ACEMMECCKBR | |
| SCHEMBL7488630 | 0.84 | ACE (0.65) | ACEMMECCKBR | |
| SCHEMBL7389206 | 0.83 | ACE (0.65) | ACEMMECCKBR | |
| SCHEMBL10200768 | 0.83 | ACE (0.67) | ACEMMECCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994894-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999007731-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1999-02-18 | — | — | WO | disclosed |