Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8062474 | 0.94 | EPAS1 (0.34) | HRH4EPAS1 | |
| SCHEMBL1384760 | 0.86 | — | — | |
| SCHEMBL7856396 | 0.84 | EPAS1 (0.32) | EPAS1 | |
| SCHEMBL7854722 | 0.84 | — | — | |
| SCHEMBL7854501 | 0.83 | EPAS1 (0.32) | EPAS1 | |
| SCHEMBL7852425 | 0.83 | EPAS1 (0.32) | EPAS1 | |
| SCHEMBL6486136 | 0.83 | EPAS1 (0.32) | EPAS1MBTD1L3MBTL3 | |
| SCHEMBL7854119 | 0.83 | EPAS1 (0.32) | EPAS1 | |
| SCHEMBL3204034 | 0.82 | — | — | |
| SCHEMBL477174 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140333-A | FOR TREATMENT AND/OR PROPHYLAXIS OF DISEASES INCLUDE SUCH RESPIRATORY DISEASES AS CHRONIC OBSTRUCTIVE PULMONARY DISEASES, CHRONIC BRONCHITIS, ASTHMA, CHRONIC RESPIRATORY OBSTRUCTION, PULMONARY FIBROSIS, PULMONARY EMPHYSEMA | BANYU PHARMACEUTICAL CO LTD (JP) | 2000-10-31 | — | — | US | disclosed |