Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.66 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.66 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.66 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057046 | 0.94 | PTGIR (0.58) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL8066934 | 0.91 | PTGIR (0.78) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL27386880 | 0.88 | PTGIR (0.72) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7959445 | 0.87 | PTGIR (0.86) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7964164 | 0.85 | PTGIR (0.68) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL8066007 | 0.85 | PTGIR (0.68) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL27520735 | 0.85 | PTGIR (0.68) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL9006955 | 0.85 | PTGIR (0.66) | PTGIRPTGER4PTGER1PTGER3ALDH1A1 | |
| SCHEMBL7959550 | 0.85 | PTGIR (0.66) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL9006951 | 0.84 | PTGIR (0.64) | PTGIRPTGER4PTGER1PTGER3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736018-B1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-6025375-A | INHIBITORY ACTIVITY ON PLATELET AGGREGATION, VASODILATING ACTIVITY, ANTIHYPERTENSIVE ACTIVITY OR THE LIKE AND ARE PROSTAGLANDIN I.SUB.2 AGONISTS, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| WO-1995017393-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-29 | — | — | WO | disclosed |