SCHEMBL8057183

SCHEMBL8057183

OC(C1=CC2CCC1C2)C1CC2CCC1C2

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.41
TDO2 P48775 1/20 0.41
HPGD P15428 2/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
POLB P06746 1/20 0.32
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6557525 0.70 HIF1A (0.36) IDO1TDO2
SCHEMBL7184444 0.65 HPGD (0.42) IDO1TDO2HPGDALDH1A1KMT2A
SCHEMBL3821014 0.65 HPGD (0.42) IDO1TDO2HPGDALDH1A1KMT2A
SCHEMBL1010889 0.64 CYP19A1 (0.31)
SCHEMBL15466797 0.62
SCHEMBL24906563 0.62 HPGD (0.40) IDO1TDO2HPGDALDH1A1KMT2A
SCHEMBL14646057 0.62 HPGD (0.47) HPGDALDH1A1KMT2APOLBLMNA
SCHEMBL24245343 0.62 HPGD (0.40) IDO1TDO2HPGDALDH1A1KMT2A
SCHEMBL3345713 0.62 HPGD (0.47) HPGDALDH1A1KMT2APOLBLMNA
SCHEMBL27822037 0.62 HPGD (0.40) IDO1TDO2HPGDALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103450-A Photosensitive polymer, dissolution inhibitor and chemically amplified photoresist composition containing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-08-15 US disclosed