Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 19/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 19/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 19/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057194 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL8068999 | 0.89 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL8068996 | 0.89 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL8057425 | 0.86 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL8057428 | 0.86 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL8057082 | 0.84 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL8057084 | 0.84 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL4032379 | 0.82 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL10432712 | 0.76 | SLC6A2 (0.77) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL10431910 | 0.76 | SLC6A2 (0.77) | SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028080-A | Quinolin-2-(1H)-ones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-02-22 | — | — | US | disclosed |