Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TOP2A | P11388 | 4/20 | 0.42 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059195 | 0.88 | KDM4E (0.48) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| SCHEMBL8046793 | 0.86 | HPGD (0.52) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| SCHEMBL8057309 | 0.86 | KDM4E (0.46) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| SCHEMBL27565253 | 0.84 | KDM4E (0.46) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| SCHEMBL8046770 | 0.82 | KDM4E (0.50) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| SCHEMBL8057434 | 0.82 | KDM4E (0.50) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| SCHEMBL8057420 | 0.81 | KDM4E (0.49) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| SCHEMBL8046660 | 0.81 | KDM4E (0.46) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| SCHEMBL8058583 | 0.79 | KDM4E (0.48) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| SCHEMBL8058568 | 0.79 | KDM4E (0.52) | KDM4EMAPK1HPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034086-A | VIRICIDES; AIDS THERAPY | UBE INDUSTRIES, LTD. | 2000-03-07 | — | — | US | disclosed |
| CN-1214632-A | Remedies or preventives for AIDS | SANKYO CO (JP) | 1999-04-21 | — | — | CN | disclosed |
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |
| CN-1152916-A | Trifluoromethylquinoline carboxylic acid derivative | UBE INDUSTRIES (JP) | 1997-06-25 | — | — | CN | disclosed |
| EP-0773214-A1 | TRIFLUOROMETHYLQUINOLINECARBOXYLIC ACID DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |