⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28202692 | 0.76 | — | — | |
| SCHEMBL8089899 | 0.74 | — | — | |
| SCHEMBL22282342 | 0.73 | — | — | |
| SCHEMBL5494935 | 0.71 | — | — | |
| SCHEMBL68505 | 0.71 | — | — | |
| SCHEMBL18745633 | 0.69 | — | — | |
| SCHEMBL12596592 | 0.69 | — | — | |
| SCHEMBL17325792 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL11759189 | 0.69 | — | — | |
| SCHEMBL8091314 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170119741-A1 | MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE | ELIXIR MEDICAL CORPORATION | 2017-05-04 | — | — | US | disclosed |
| US-9149470-B2 | Macrocyclic lactone compounds and methods for their use | ELIXIR MEDICAL CORPORATION (US) | 2015-10-06 | — | — | US | disclosed |
| US-20120071500-A1 | MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE | ELIXIR MEDICAL CORPORATION (US) | 2012-03-22 | — | — | US | disclosed |
| US-8088789-B2 | Administering hemiketal ring and seco-macrocyclic lactones; immunosuppressive, anti-proliferative, anti-fungal and anti-tumor | ELIXIR MEDICAL CORPORATION (US) | 2012-01-03 | — | — | US | disclosed |
| US-20080234309-A1 | MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE | ELIXIR MEDICAL CORPORATION (US) | 2008-09-25 | — | — | US | disclosed |