Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 18/20 | 0.60 |
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805896 | 0.87 | SCN9A (0.66) | SCN9AFPR2 | |
| SCHEMBL14919880 | 0.83 | SCN9A (0.64) | SCN9AFPR2 | |
| SCHEMBL14920119 | 0.82 | SCN9A (0.62) | SCN9AFPR2 | |
| SCHEMBL805895 | 0.81 | SCN9A (0.64) | SCN9AFPR2 | |
| SCHEMBL15383816 | 0.79 | SCN9A (0.59) | SCN9AFPR2 | |
| SCHEMBL3143887 | 0.76 | SCN9A (0.61) | SCN9ASCN4A | |
| SCHEMBL13270540 | 0.76 | SCN9A (0.50) | SCN9AFPR2SCN4A | |
| SCHEMBL14921893 | 0.76 | SCN9A (0.74) | SCN9AFPR2 | |
| SCHEMBL21236955 | 0.76 | SCN9A (0.67) | SCN9AFPR2 | |
| SCHEMBL14920078 | 0.74 | SCN9A (0.60) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616441-B1 | PYRIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA LP (US) | 2019-08-07 | — | — | EP | disclosed |
| WO-2012035421-A2 | PYRIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA L.P. (US) | 2012-03-22 | — | — | WO | disclosed |