Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.36 |
| ▸ | PDE4A | P27815 | 5/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798745 | 0.83 | KAT2B (0.52) | KAT2BBAZ2BSYKPDE4DPDE4A | |
| SCHEMBL24498738 | 0.74 | KAT2B (0.43) | KAT2BBAZ2BPDE4DPDE4APDE4B | |
| SCHEMBL1929230 | 0.74 | KAT2B (0.53) | KAT2BBAZ2BSYKPDE4DPDE4A | |
| SCHEMBL19837798 | 0.74 | KAT2B (0.56) | KAT2BBAZ2BSYKPDE4DPDE4A | |
| SCHEMBL12181083 | 0.74 | SLC6A2 (0.53) | KAT2BBAZ2BSYKPSEN1PSEN2 | |
| SCHEMBL3798831 | 0.74 | KAT2B (0.53) | KAT2BBAZ2BSYKPDE4DPDE4A | |
| SCHEMBL12180578 | 0.74 | KAT2B (0.56) | KAT2BBAZ2BSYKPDE4DPDE4A | |
| SCHEMBL8663839 | 0.74 | SLC6A4 (0.56) | KAT2BBAZ2BSYKNR1I2HSD11B1 | |
| SCHEMBL674990 | 0.74 | KAT2B (0.53) | KAT2BBAZ2BSYKPDE4DPDE4A | |
| SCHEMBL22040926 | 0.72 | KAT2B (0.45) | KAT2BBAZ2BSYKPDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |