Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049345 | 0.95 | CMA1 (0.90) | CMA1CTSG | |
| SCHEMBL8059762 | 0.94 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL8049426 | 0.94 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL8066011 | 0.92 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL8060543 | 0.92 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL8061810 | 0.91 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL8059793 | 0.91 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL7152045 | 0.91 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL5622046 | 0.91 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL31061253 | 0.91 | CMA1 (1.00) | CMA1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080738-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE USED FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II | YOSHITOMI PHARMACEUTICALS INDUSTRIES, LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0940400-A1 | NOVEL HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USES THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-08 | — | — | EP | disclosed |