Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1568477 | 0.81 | CYP1A2 (0.54) | CYP1A2MAPTKMT2AKCNN4CYP2C19 | |
| SCHEMBL1414646 | 0.81 | CYP1A2 (0.48) | CYP1A2MAPTKMT2AKCNN4CYP2C19 | |
| SCHEMBL11884455 | 0.77 | MAPT (0.46) | CYP1A2MAPTKMT2AKCNN4CYP2C19 | |
| SCHEMBL25968774 | 0.77 | MAPT (0.58) | CYP1A2MAPTKMT2AKCNN4CYP2C19 | |
| SCHEMBL2927951 | 0.77 | CYP2C9 (0.50) | CYP1A2MAPTKMT2AKCNN4CYP2C19 | |
| SCHEMBL31380243 | 0.77 | CYP1A2 (0.44) | CYP1A2MAPTKMT2AKCNN4CYP2C19 | |
| SCHEMBL11812791 | 0.75 | HDAC3 (0.57) | CYP1A2MAPTKMT2AKCNN4CYP2C19 | |
| SCHEMBL3174356 | 0.73 | KCNN4 (0.69) | CYP1A2MAPTKMT2AKCNN4CYP2C19 | |
| SCHEMBL11536202 | 0.73 | KMT2A (0.48) | CYP1A2MAPTKMT2AKCNN4CYP2C19 | |
| SCHEMBL16267608 | 0.73 | PTPN1 (0.46) | CYP1A2MAPTKMT2AKCNN4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674232-B1 | Recording sheets | XEROX CORP (US) | 2000-05-31 | — | — | EP | claimed |
| US-5663022-A | Recording sheets | XEROX CORPORATION (US) | 1997-09-02 | — | — | US | claimed |
| EP-0674232-A2 | Recording sheets | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
| US-4254285-A | 1-Hydroxymethyl-1-1-oxo prostane derivatives of the E and F series | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4250325-A | ANTISECRETORY, BRONCHODILATOR, ANTIFERTILITY, AND ANTIINFLAMMATORY AGENTS; OXYTOCICS; MUSCLE STIMULANTS | AMERICAN CYANAMID COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| EP-0013107-A1 | 16-Hydroxy-16-vinyl (or cyclopropyl)-prostan-1-ols and pharmaceutical compositions containing the same | AMERICAN CYANAMID COMPANY (US) | 1980-07-09 | — | — | EP | disclosed |
| US-4206151-A | BRONCHODILATOR, ANTISECRETORY, HYPOTENSIVE | AMERICAN CYANAMID COMPANY (US) | 1980-06-03 | — | — | US | disclosed |
| EP-0002590-A1 | Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |