Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 17/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421429 | 0.90 | SCN9A (1.00) | SCN9A | |
| SCHEMBL787559 | 0.90 | SCN9A (1.00) | SCN9A | |
| SCHEMBL787336 | 0.87 | SCN9A (1.00) | SCN9A | |
| SCHEMBL787334 | 0.87 | SCN9A (1.00) | SCN9A | |
| SCHEMBL805932 | 0.82 | SCN9A (0.82) | SCN9AMCL1 | |
| SCHEMBL787511 | 0.81 | SCN9A (0.83) | SCN9A | |
| SCHEMBL29421490 | 0.81 | SCN9A (1.00) | SCN9AMCL1 | |
| SCHEMBL788021 | 0.81 | SCN9A (1.00) | SCN9AMCL1 | |
| SCHEMBL17082881 | 0.74 | SCN9A (1.00) | SCN9A | |
| SCHEMBL787201 | 0.74 | SCN9A (0.89) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035421-A2 | PYRIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA L.P. (US) | 2012-03-22 | — | — | WO | disclosed |