Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056274 | 0.83 | HTR2B (0.46) | HTR2BHTR7 | |
| SCHEMBL8060754 | 0.82 | HTR2B (0.41) | SLC9A1HTR2BHTR7 | |
| SCHEMBL8045374 | 0.82 | HTR2B (0.46) | HTR2BHTR7 | |
| SCHEMBL8045075 | 0.82 | HTR2B (0.48) | HTR2BHTR7 | |
| SCHEMBL8063051 | 0.81 | — | — | |
| SCHEMBL8045040 | 0.81 | HTR2B (0.44) | HTR2BHTR7 | |
| SCHEMBL8062798 | 0.80 | SLC6A2 (0.46) | SLC6A3 | |
| SCHEMBL8060820 | 0.80 | HTR2B (0.41) | HTR2BHTR7 | |
| SCHEMBL8057135 | 0.78 | HTR2B (0.41) | SLC9A1HTR2BHTR7CYP3A4CYP2C9 | |
| SCHEMBL8060778 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028069-A | Heterocyclyl-condensed benzoylguanidines, their production and use as inhibitors of the cellular Na+/H+-antiporter | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKER HAFTUNG (DE) | 2000-02-22 | — | — | US | disclosed |