Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinimide SCHEMBL3262638 | 1.00 | CRBN (0.65) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL169754 | 1.00 | CRBN (0.65) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL28381869 | 1.00 | CRBN (0.65) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL6823086 | 0.97 | CRBN (0.61) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL898832 | 0.97 | CRBN (0.61) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL18397679 | 0.92 | CRBN (0.55) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL4554085 | 0.90 | CRBN (0.52) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL73277 | 0.85 | CRBN (0.52) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL25422802 | 0.84 | CRBN (0.46) | CRBNCYP2C19CA9 | |
| SCHEMBL28758633 | 0.83 | CRBN (0.43) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124247-A | Use of borated compounds for the improvement of the compatibility of lubricating oils with fluorocarbon elastomers | CHEVRON CHEMICAL S.A. (FR) | 2000-09-26 | — | — | US | disclosed |