Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456213 | 0.81 | CHRM2 (0.33) | KCNH2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7460935 | 0.74 | HTR1D (0.30) | — | |
| SCHEMBL7454062 | 0.69 | — | — | |
| SCHEMBL8061015 | 0.56 | KCNH2 (0.38) | KCNH2LPLLIPGCYP2E1CYP2A6 | |
| SCHEMBL29136542 | 0.56 | CYP2A6 (0.59) | KCNH2LPLLIPGCYP2E1CYP2A6 | |
| SCHEMBL27989815 | 0.55 | CYP2A6 (0.74) | KCNH2LPLLIPGCYP2E1CYP2A6 | |
| SCHEMBL3157632 | 0.54 | CYP2A6 (0.41) | KCNH2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28167019 | 0.54 | KCNH2 (0.52) | KCNH2LPLLIPGCYP2E1CYP2A6 | |
| Formaldehyde SCHEMBL28680174 | 0.53 | CYP2A6 (0.62) | KCNH2LPLLIPGCYP2E1CYP2A6 | |
| SCHEMBL14451036 | 0.53 | PDGFRB (0.53) | KCNH2CYP2E1CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6132475-A | FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-10-17 | — | — | US | disclosed |