SCHEMBL8061024

SCHEMBL8061024

COc1cccc2c(C(=O)c3ccc(F)c4ccccc34)c(C)n(CCN3CCOCC3)c12

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 12/20 0.80
CNR1 P21554 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8071354 0.89 CNR2 (0.80) CNR2CNR1
SCHEMBL8060941 0.89 CNR2 (1.00) CNR2CNR1
SCHEMBL7782596 0.88 CNR2 (0.78) CNR2CNR1
SCHEMBL10660781 0.82 CNR1 (0.74) CNR2CNR1
SCHEMBL8075118 0.81 CNR2 (0.77) CNR2CNR1
SCHEMBL9691491 0.79 CNR1 (0.74) CNR2CNR1
SCHEMBL9036598 0.78 CNR1 (0.73) CNR2CNR1
SCHEMBL8075206 0.77 CNR2 (0.80) CNR2CNR1
SCHEMBL8071560 0.76 CNR2 (0.73) CNR2CNR1
SCHEMBL10093007 0.74 CNR2 (0.77) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833818-A1 CB 2? RECEPTOR AGONIST COMPOUNDS SANOFI (FR) 1998-04-08 EP claimed
WO-1997000860-A1 CB2 RECEPTOR AGONIST COMPOUNDS SANOFI (FR) 1997-01-09 WO claimed
US-6013648-A IMMUNOMODULATORS SANOFI (FR) 2000-01-11 US disclosed
WO-1997000860-A1 CB2 RECEPTOR AGONIST COMPOUNDS SANOFI (FR) 1997-01-09 WO disclosed