Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.42 |
| ▸ | CMA1 | P23946 | 7/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14232792 | 1.00 | ELANE (0.42) | ELANECMA1ACEKLK5F2 | |
| SCHEMBL8055611 | 1.00 | ELANE (0.42) | ELANECMA1ACEKLK5F2 | |
| SCHEMBL26121717 | 0.89 | ACE (0.51) | ELANECMA1ACEF2 | |
| SCHEMBL159043 | 0.89 | ACE (0.51) | ELANECMA1ACEF2 | |
| SCHEMBL806133 | 0.89 | ACE (0.51) | ELANECMA1ACEF2 | |
| SCHEMBL1300341 | 0.89 | ACE (0.51) | ELANECMA1ACEF2 | |
| SCHEMBL8140568 | 0.88 | ELANE (0.39) | ELANECMA1 | |
| SCHEMBL14202917 | 0.88 | KLK5 (0.51) | ELANECMA1ACEKLK5 | |
| SCHEMBL8046113 | 0.88 | KLK5 (0.51) | ELANECMA1ACEKLK5 | |
| SCHEMBL14235324 | 0.87 | CMA1 (0.44) | ELANECMA1ACEKLK5F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037259-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011041551-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | INTERMUNE, INC. (US) | 2011-04-07 | — | — | WO | disclosed |