Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078247 | 1.00 | NQO1 (0.52) | NQO1MAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8063380 | 1.00 | NQO1 (0.52) | NQO1MAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8071429 | 1.00 | NQO1 (0.52) | NQO1MAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8062743 | 1.00 | NQO1 (0.52) | NQO1MAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8070892 | 0.98 | NQO1 (0.54) | NQO1MAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8070933 | 0.92 | NQO1 (0.56) | NQO1MAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL10575040 | 0.90 | NQO1 (0.64) | NQO1MAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL4248652 | 0.88 | NQO1 (0.67) | NQO1MAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8076372 | 0.87 | MEN1 (0.60) | ALDH1A1LMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8076106 | 0.87 | MEN1 (0.60) | ALDH1A1LMNAKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |