Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073049 | 1.00 | SPHK2 (0.48) | SPHK2SPHK1TDP1USP2ALDH1A1 | |
| SCHEMBL8070908 | 1.00 | SPHK2 (0.48) | SPHK2SPHK1TDP1USP2ALDH1A1 | |
| SCHEMBL8072635 | 1.00 | SPHK2 (0.48) | SPHK2SPHK1TDP1USP2ALDH1A1 | |
| SCHEMBL8072128 | 0.98 | SPHK2 (0.45) | SPHK2SPHK1TDP1USP2ALDH1A1 | |
| SCHEMBL8073139 | 0.92 | SPHK2 (0.40) | SPHK2SPHK1TDP1USP2ALDH1A1 | |
| SCHEMBL11336193 | 0.89 | TDP1 (0.52) | TDP1USP2ALDH1A1HPGDHDAC1 | |
| SCHEMBL12989712 | 0.89 | TDP1 (0.52) | TDP1USP2ALDH1A1HPGDHDAC1 | |
| SCHEMBL11328438 | 0.87 | TDP1 (0.48) | TDP1USP2ALDH1A1HPGDHDAC1 | |
| SCHEMBL8063283 | 0.83 | CYP3A4 (0.38) | SPHK2SPHK1 | |
| SCHEMBL28284957 | 0.82 | SPHK2 (0.46) | SPHK2SPHK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |