SCHEMBL8064284

SCHEMBL8064284

CCOC(=O)C1NCCC1Oc1c(F)c(Oc2cccc(C3=NCCN3C)c2)nc(Oc2cc(C(=N)N)ccc2O)c1F

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.76
F2 P00734 13/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6579697 0.87 F10 (1.00) F10F2
SCHEMBL6578739 0.85 F10 (0.89) F10F2
SCHEMBL7960969 0.84 F10 (0.70) F10F2
SCHEMBL6576669 0.84 F10 (1.00) F10F2
SCHEMBL6576289 0.84 F10 (0.77) F10F2
SCHEMBL6579641 0.84 F10 (0.74) F10F2
SCHEMBL6578537 0.83 F10 (0.81) F10F2
SCHEMBL7546310 0.83 F10 (0.79) F10F2
SCHEMBL6773407 0.83 F10 (0.81) F10F2
SCHEMBL6576586 0.83 F10 (0.76) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6034103-A THROMBOSIS THERAPY BERLEX LABORATORIES, INC. (US) 2000-03-07 US disclosed
US-5889005-A Benzamidine derivatives and their use for treating thrombotic diseases BERLEX LABORATORIES, INC. (US) 1999-03-30 US disclosed
US-5883100-A Benzamidine derivatives and their use as anti-coagulants BERLEX LABORATORIES, INC. (US) 1999-03-16 US disclosed
US-5877181-A Benzamidine derivatives and their use as anti-coagulants BERLEX LABORATORIES, INC. (US) 1999-03-02 US disclosed
US-5691364-A Benzamidine derivatives and their use as anti-coagulants BERLEX LABORATORIES, INC. (US) 1997-11-25 US disclosed