⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23141888 | 1.00 | — | — | |
| SCHEMBL22804154 | 0.90 | — | — | |
| SCHEMBL7390 | 0.90 | — | — | |
| SCHEMBL6230707 | 0.75 | — | — | |
| SCHEMBL125215 | 0.75 | — | — | |
| SCHEMBL19100153 | 0.71 | — | — | |
| SCHEMBL28076178 | 0.69 | — | — | |
| SCHEMBL176040 | 0.67 | CHRM2 (0.39) | — | |
| SCHEMBL9682157 | 0.65 | — | — | |
| SCHEMBL24752922 | 0.65 | CHRM2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8487 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417382-B1 | — | — | None | — | — | US | claimed |
| US-20240238241-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF PANCREATIC CANCER AND BILE DUCT CANCER | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2024-07-18 | — | — | US | claimed |
| WO-2024141444-A1 | NEW BENZIMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-04 | — | — | WO | claimed |
| US-20240197711-A1 | Combination Therapy for Cancer Treatment | REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-06-20 | — | — | US | claimed |
| CN-114181205-B | Pyrazolopyridine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-06-11 | — | — | CN | claimed |
| EP-4378481-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF PANCREATIC CANCER AND BILE DUCT CANCER | Japan Science and Technology Agency (JP) | 2024-06-05 | — | — | EP | claimed |
| US-20240156778-A1 | THIOPHENE DERIVATIVES FOR USE IN TREATING PORTAL INFLAMMATION AND FIBROSIS | ENYO PHARMA (FR) | 2024-05-16 | — | — | US | claimed |
| US-20240124419-A1 | SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-04-18 | — | — | US | claimed |
| CN-117794576-A | Pharmaceutical composition for treating pancreatic cancer and cholangiocarcinoma | 国立研究开发法人科学技术振兴机构 | 2024-03-29 | — | — | CN | claimed |
| EP-4328219-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-02-28 | — | — | EP | claimed |
| US-3975406-A | Hexahydro-5-oxy-2-loweralkoxy-2H-cyclopenta[b]-furan-4-carbonitrile intermediates for prostaglandins | MAYER HANS JOHANN | 1976-08-17 | — | — | US | claimed |
| US-3975399-A | PROSTAGLANDIN LIKE ACTIVITY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-17 | — | — | US | claimed |
| US-3974185-A | Hexahydro-cyclopentano[b]furans having a 2-C.tbd.C containing substituent in the 4-position | HOFFMANN-LA ROCHE INC. (US) | 1976-08-10 | — | — | US | claimed |
| US-3972906-A | Novel - 11-substituted steroids of the estrane series | AKZONA INCORPORATED (US) | 1976-08-03 | — | — | US | claimed |
| US-3970674-A | Certain hexahydro-2-loweralkoxy-5-oxycyclopenta [b] furans containing an olefinic substituent in the 4-position | HOFFMANN-LA ROCHE INC. (US) | 1976-07-20 | — | — | US | claimed |
| US-3956316-A | PROGESTATIONAL AND SALT-RETAINING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-11 | — | — | US | claimed |
| US-3954811-A | PROSTAGLANDIN INTERMEDIATES | SUMITOMO CHEMICAL CO., LTD. (JA) | 1976-05-04 | — | — | US | claimed |
| US-3950406-A | BRONCHODILATORS, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-04-13 | — | — | US | claimed |
| US-3940425-A | Process for the production of polyunsaturated compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-24 | — | — | US | claimed |
| US-3937700-A | Novel 1,2-methylene-17α-acyloxy (or improved hydroxy)-9β, 10α-steroid compounds of the pregnane series, pharmaceutic preparations on the basis of the novel compounds and methods of producing said compounds and preparations | U.S. PHILIPS CORPORATION (US) | 1976-02-10 | — | — | US | claimed |