⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606948 | 0.76 | — | — | |
| SCHEMBL12239876 | 0.72 | — | — | |
| SCHEMBL16238142 | 0.72 | KDM4E (0.41) | — | |
| SCHEMBL28454671 | 0.70 | — | — | |
| SCHEMBL23735488 | 0.67 | KDM4E (0.44) | — | |
| Acetohydroxamic Acid SCHEMBL14492 | 0.67 | — | — | |
| SCHEMBL18510170 | 0.67 | — | — | |
| SCHEMBL4397 | 0.67 | — | — | |
| SCHEMBL1276127 | 0.67 | — | — | |
| SCHEMBL20411614 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303625-A1 | CYCLIC POLYPEPTIDES FOR PCSK9 INHIBITION | RA PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | US | disclosed |
| CN-109251935-A | White backed planthopper phosphorus acetylglucosamine mutase gene segment and its application | 凯里学院 | 2019-01-22 | — | — | CN | disclosed |
| WO-2017181134-A2 | DETECTING CANCER DRIVER GENES AND PATHWAYS | F. HOFFMAN-LA ROCHE AG (CH) | 2017-10-19 | — | — | WO | disclosed |
| US-9695208-B2 | Sialic acid (A-(2-6))-D-aminopyranose derivatives, synthesis methods and uses thereof | PEKING UNIVERSITY (CN) | 2017-07-04 | — | — | US | disclosed |
| US-20160251407-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2016-09-01 | — | — | US | disclosed |
| US-9393330-B2 | Compounds for use in diagnosing and treating melanoma, including metastatic melanoma and methods related to same | STC.UNM (US) | 2016-07-19 | — | — | US | disclosed |
| US-20140147385-A1 | COMPOUNDS FOR USE IN DIAGNOSING AND TREATING MELANOMA, INCLUDING METASTATIC MELANOMA AND METHODS RELATED TO SAME | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2014-05-29 | — | — | US | disclosed |
| US-8585972-B2 | Biosensor | FUJIFILM CORPORATION (JP) | 2013-11-19 | — | — | US | disclosed |
| US-20100221845-A1 | BIOSENSOR | FUJIFILM CORPORATION (JP) | 2010-09-02 | — | — | US | disclosed |
| EP-1017480-A1 | METHOD FOR SEPARATING ACTINIDES AND LANTHANIDES BY MEMBRANE TRANSPORT USING A CALIXARENE | Commissariat à l'Energie Atomique (FR) | 2000-07-12 | — | — | EP | disclosed |
| EP-1007747-A1 | METHOD FOR SEPARATING ACTINIDES AND LANTHANIDES BY LIQUID-LIQUID EXTRACTION USING CALIXARENES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999010545-A1 | METHOD FOR SEPARATING ACTINIDES AND LANTHANIDES BY LIQUID-LIQUID EXTRACTION USING CALIXARENES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1999-03-04 | — | — | WO | disclosed |
| WO-1999010087-A1 | METHOD FOR SEPARATING ACTINIDES AND LANTHANIDES BY MEMBRANE TRANSPORT USING A CALIXARENE | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1999-03-04 | — | — | WO | disclosed |