SCHEMBL8065323

SCHEMBL8065323

CN(C)C(=O)c1cccc(OC(F)CC(Br)Oc2nc(Oc3cc(C(=N)N)ccc3O)c(F)cc2F)c1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.62
F2 P00734 11/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6576443 0.86 F10 (0.82) F10F2
SCHEMBL6579021 0.80 F10 (0.72) F10F2
SCHEMBL6578787 0.79 F10 (0.71) F10F2
SCHEMBL6581044 0.79 F10 (0.73) F10F2
SCHEMBL6579222 0.78 F10 (0.88) F10F2
SCHEMBL6578782 0.78 F10 (0.74) F10F2
SCHEMBL6578534 0.77 F10 (1.00) F10F2
SCHEMBL6581040 0.77 F10 (0.75) F10F2
SCHEMBL6578967 0.77 F10 (0.84) F10F2
SCHEMBL6579015 0.76 F10 (0.71) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6034103-A THROMBOSIS THERAPY BERLEX LABORATORIES, INC. (US) 2000-03-07 US disclosed