SCHEMBL8066002

SCHEMBL8066002

COC(C)Oc1nsnc1OC1CN2CCC1C2

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 12/20 0.55
CHRM2 P08172 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8063977 0.87 CHRM1 (0.55) CHRM1CHRM2
SCHEMBL6781184 0.78 CHRM1 (0.66) CHRM1CHRM2
SCHEMBL7808671 0.75 CHRM1 (0.42) CHRM1CHRM2
SCHEMBL6784125 0.74 CHRM1 (0.41) CHRM1CHRM2
SCHEMBL6784661 0.74 CHRM1 (0.58) CHRM1CHRM2
SCHEMBL6786827 0.73 CHRM1 (0.42) CHRM1CHRM2
SCHEMBL6786920 0.73 CHRM1 (0.42) CHRM1CHRM2
SCHEMBL6791897 0.73 CHRM1 (0.42) CHRM1CHRM2
SCHEMBL6783855 0.73 CHRM1 (0.42) CHRM1CHRM2
SCHEMBL7811374 0.73 CHRM1 (0.58) CHRM1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6069159-A USEFUL AS STIMULANTS OF THE COGNITIVE FUNCTION OF THE FOREBRAIN AND HIPPOCAMPUS OF MAMMALS ELI LILLY AND COMPANY (US) 2000-05-30 US disclosed