SCHEMBL8066287

SCHEMBL8066287

CN(C)CCOCCOCC(O)COCCOCCN(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
HSD17B10 Q99714 1/20 0.38
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRM3 P20309 1/20 0.35
CHRNA4 P43681 1/20 0.35
USP2 O75604 2/20 0.35
SPHK1 Q9NYA1 1/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
HTT P42858 1/20 0.34
KDM4E B2RXH2 7/20 0.34
ALDH1A1 P00352 4/20 0.34
LPAR5 Q9H1C0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7531837 0.95 HSD17B10 (0.41) CA12CA1CA2CA9HSD17B10
SCHEMBL19577727 0.87 HSD17B10 (0.40) CA12CA1CA2CA9HSD17B10
SCHEMBL4249632 0.84 USP2 (0.52) CA12CA1CA2CA9HSD17B10
SCHEMBL20041604 0.84 HSD17B10 (0.41) CA12CA1CA2CA9HSD17B10
SCHEMBL10884401 0.84 HSD17B10 (0.41) CA12CA1CA2CA9HSD17B10
SCHEMBL7204254 0.84 HSD17B10 (0.41) CA12CA1CA2CA9HSD17B10
SCHEMBL8122987 0.83 CA12 (0.44) CA12CA1CA2CA9HSD17B10
SCHEMBL17261675 0.83 CA1 (0.36) CA12CA1CA2CA9HSD17B10
SCHEMBL7527905 0.82 USP2 (0.44) HSD17B10USP2SPHK1HTTKDM4E
SCHEMBL21727220 0.81 CA1 (0.52) CA12CA1CA2CA9HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0582166-B2 Multifuctional resins without chlorine for paper finishing BAYER AG (DE) 2000-08-23 EP disclosed
US-5739249-A POLYUREAURETHANE COPOLYMER BAYER AKTIENGESELLSCHAFT (DE) 1998-04-14 US disclosed
US-5503714-A POLYISOCYANATES HAVING TERTIARY AMINO OR AMMONIUM GROUPS; WET AND DRY STRENGTH BAYER AKTIENGESELLSCHAFT (DE) 1996-04-02 US disclosed
EP-0582166-A1 Multifuctional resins without chlorine for paper finishing BAYER AG (DE) 1994-02-09 EP disclosed