SCHEMBL8066396

SCHEMBL8066396

CCCCCc1ccc(C(=O)Oc2cc(F)c(C#N)c(F)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RARB P10826 8/20 0.46
MAPT P10636 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
THRB P10828 6/20 0.44
THRA P10827 5/20 0.44
RARA P10276 2/20 0.43
RARG P13631 1/20 0.43
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MTOR P42345 1/20 0.42
KMT2A Q03164 1/20 0.42
PRSS1 P07477 1/20 0.42
ACR P10323 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1367878 0.97 RARB (0.49) RARBMAPTSMN1; SMN2THRBTHRA
SCHEMBL14525759 0.96 RARB (0.42) RARBMAPTSMN1; SMN2THRBTHRA
SCHEMBL11911605 0.96 RARB (0.50) RARBMAPTSMN1; SMN2THRBTHRA
SCHEMBL11893340 0.96 RARB (0.50) RARBMAPTSMN1; SMN2THRBTHRA
SCHEMBL11893371 0.96 RARB (0.50) RARBMAPTSMN1; SMN2THRBTHRA
SCHEMBL11893343 0.96 RARB (0.50) RARBMAPTSMN1; SMN2THRBTHRA
SCHEMBL11893423 0.96 RARB (0.50) RARBMAPTSMN1; SMN2THRBTHRA
SCHEMBL11893359 0.96 RARB (0.50) RARBMAPTSMN1; SMN2THRBTHRA
SCHEMBL11893604 0.93 RARB (0.48) RARBMAPTSMN1; SMN2THRBTHRA
SCHEMBL8509611 0.91 MAPT (0.44) MAPTSMN1; SMN2THRBALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119955669-A Gordonia and application thereof 东莞理工学院 2025-05-09 CN disclosed
US-10920145-B2 Method for obtaining a material comprising a liquid crystal mix with a stabilized blue phase and optical article comprising this material ESSILOR INTERNATIONAL (FR) 2021-02-16 US disclosed
US-20180237694-A1 METHOD FOR OBTAINING A MATERIAL COMPRISING A LIQUID CRYSTAL MIX WITH A STABILIZED BLUE PHASE AND OPTICAL ARTICLE COMPRISING THIS MATERIAL ESSILOR INTERNATIONAL (FR) 2018-08-23 US disclosed
EP-3115436-A1 METHOD FOR OBTAINING A MATERIAL COMPRISING A LIQUID CRYSTAL MIX WITH A STABILIZED BLUE PHASE AND OPTICAL ARTICLE COMPRISING THIS MATERIAL ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2017-01-11 EP disclosed
US-9371485-B2 Liquid crystal composition, liquid crystal element, and liquid crystal display device Semiconductor Energy Laboraory Co., LTD. (JP) 2016-06-21 US disclosed
US-9371485-B2 Liquid crystal composition, liquid crystal element, and liquid crystal display device Semiconductor Energy Laboraory Co., LTD. (JP) 2016-06-21 US disclosed
US-9175220-B2 High scattering smectic liquid crystal material and display device using the same HALATION PHOTONICS CORPORATION (CN) 2015-11-03 US disclosed
US-20150210924-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2015-07-30 US disclosed
US-20150210924-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2015-07-30 US disclosed
US-9053675-B2 Signal line driver circuit and liquid crystal display device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-09 US disclosed
WO-2013012020-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-24 WO disclosed
WO-2013012020-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-24 WO disclosed
WO-2013008657-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-17 WO disclosed
WO-2013008657-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-17 WO disclosed
US-20130009094-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-10 US disclosed
US-20130009094-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-10 US disclosed
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 US disclosed
EP-1010687-A2 Ester derivative, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 2000-06-21 EP disclosed
US-5755994-A LARGE DIELECTRIC ANISOTROPIC CHISSO CORPORATION (JP) 1998-05-26 US disclosed
EP-0738709-A2 Ester derivate, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1996-10-23 EP disclosed