⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068744 | 0.95 | — | — | |
| SCHEMBL8068770 | 0.89 | — | — | |
| SCHEMBL8784817 | 0.87 | KDM4E (0.69) | — | |
| SCHEMBL8067600 | 0.87 | — | — | |
| SCHEMBL8784203 | 0.85 | — | — | |
| SCHEMBL8784968 | 0.84 | — | — | |
| SCHEMBL8066543 | 0.83 | — | — | |
| SCHEMBL8784171 | 0.83 | — | — | |
| SCHEMBL8784180 | 0.83 | — | — | |
| SCHEMBL8784053 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028080-A | Quinolin-2-(1H)-ones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-02-22 | — | — | US | disclosed |
| EP-0885196-A1 | CHINOLINE-2-(1H)-ONES | MERCK PATENT GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997026244-A1 | CHINOLINE-2-(1H)-ONES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1997-07-24 | — | — | WO | disclosed |