Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10897294 | 0.83 | TSHR (0.67) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL10445559 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL29106733 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL29996006 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL8129817 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL25997689 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL8081413 | 0.80 | HPGD (0.56) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL10022853 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL15797706 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL13147651 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031629-A2 | Method of preparation of stereoisomeric carboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-30 | — | — | EP | disclosed |