Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.82 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067771 | 1.00 | POLB (0.82) | POLBTSHRATMALDH1A1TP53 | |
| SCHEMBL14225120 | 0.96 | POLB (0.89) | POLBTSHRATMALDH1A1TP53 | |
| SCHEMBL19355164 | 0.96 | POLB (0.89) | POLBTSHRATMALDH1A1TP53 | |
| SCHEMBL16869915 | 0.90 | POLB (1.00) | POLBTSHRATMALDH1A1HTT | |
| SCHEMBL16866274 | 0.90 | POLB (1.00) | POLBTSHRATMALDH1A1HTT | |
| SCHEMBL16869924 | 0.90 | POLB (1.00) | POLBTSHRATMALDH1A1HTT | |
| SCHEMBL16870078 | 0.90 | POLB (1.00) | POLBTSHRATMALDH1A1HTT | |
| SCHEMBL19201560 | 0.86 | POLB (0.78) | POLBTSHRATMALDH1A1TP53 | |
| SCHEMBL15769078 | 0.83 | POLB (0.70) | POLBTSHRATMALDH1A1TP53 | |
| SCHEMBL15783737 | 0.82 | POLB (0.68) | POLBTSHRATMALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096755-A | N-substituted azabicycloalkane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-01 | — | — | US | disclosed |
| US-5908844-A | N-substituted azabicycloalkane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-01 | — | — | US | disclosed |
| US-5703091-A | N-substituted azabicycloalkane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |