Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 4/20 | 0.57 |
| ▸ | F10 | P00742 | 3/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387221 | 0.91 | LSS (0.59) | LSSF10CHRM1USP2LMNA | |
| SCHEMBL7498568 | 0.90 | LSS (0.58) | LSSF10CHRM1USP2LMNA | |
| SCHEMBL1387346 | 0.88 | LSS (0.58) | LSSF10CHRM1USP2LMNA | |
| SCHEMBL1387358 | 0.83 | LSS (0.81) | LSSF10CHRM1USP2LMNA | |
| SCHEMBL1387218 | 0.83 | F10 (0.61) | LSSF10CHRM1USP2LMNA | |
| SCHEMBL1387169 | 0.83 | LSS (0.53) | LSSF10LMNA | |
| SCHEMBL7404632 | 0.81 | F10 (0.50) | LSSF10CHRM1 | |
| SCHEMBL7448914 | 0.80 | F10 (0.49) | LSSF10CHRM1 | |
| SCHEMBL6793676 | 0.80 | LSS (0.74) | LSSF10CHRM1USP2LMNA | |
| SCHEMBL6791566 | 0.80 | F10 (0.60) | LSSF10CHRM1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022869-A | Aminoheterocyclic compounds with antithrombotic/anticoagulant effect | ZENECA LIMITED (GB) | 2000-02-08 | — | — | US | disclosed |