SCHEMBL8068060

SCHEMBL8068060

O=C1CCC2CC(=O)CC=C2C1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.33
MAPT P10636 2/20 0.33
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11593529 0.78 MAPT (0.44) ESR2MAPT
SCHEMBL11417033 0.76 MAPT (0.40) ESR2MAPT
SCHEMBL2208026 0.76 MAPT (0.43) ESR2MAPT
SCHEMBL3975744 0.75 DAO (0.34) MAPTGAA
SCHEMBL11688485 0.73 ESR2 (0.42) ESR2MAPT
SCHEMBL17633061 0.69 MAPT (0.44) MAPTGAA
SCHEMBL27370488 0.69 ESR2 (0.32) ESR2
SCHEMBL22728561 0.68 ESR2 (0.31) ESR2
SCHEMBL10894123 0.66 PDE4A (0.33) GAA
SCHEMBL15437891 0.65 MAPT (0.41) ESR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000239214-A DECAHYDRONAPHTHALENE DERIVATIVE AND ITS PRODUCTION DAINIPPON INK & CHEM INC 2000-09-05 JP disclosed