Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229041 | 0.86 | TSHR (0.52) | LOXL2TSHRCYP4F2CYP4A11RAB9A | |
| SCHEMBL935780 | 0.86 | TSHR (0.52) | LOXL2TSHRCYP4F2CYP4A11RAB9A | |
| SCHEMBL8068576 | 0.86 | TSHR (0.52) | LOXL2TSHRCYP4F2CYP4A11RAB9A | |
| SCHEMBL243660 | 0.85 | TSHR (0.50) | LOXL2TSHRCYP4F2CYP4A11RAB9A | |
| SCHEMBL10609523 | 0.83 | TSHR (0.52) | LOXL2TSHRCYP4F2CYP4A11RAB9A | |
| SCHEMBL307688 | 0.82 | TSHR (0.56) | LOXL2TSHRCYP4F2CYP4A11RAB9A | |
| SCHEMBL8236993 | 0.82 | SLC7A5 (0.48) | LOXL2TSHRCYP4F2CYP4A11RAB9A | |
| SCHEMBL84441 | 0.81 | TSHR (0.53) | LOXL2TSHRCYP4F2CYP4A11RAB9A | |
| SCHEMBL4407209 | 0.81 | TSHR (0.53) | LOXL2TSHRCYP4F2CYP4A11RAB9A | |
| SCHEMBL2650423 | 0.81 | TSHR (0.53) | LOXL2TSHRCYP4F2CYP4A11RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156817-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |