Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7032311 | 0.88 | KMT2A (0.39) | KMT2AMEN1TDP1ALDH1A1TP53 | |
| SCHEMBL12752205 | 0.88 | KMT2A (0.48) | KMT2AMEN1TDP1ALDH1A1KDM4E | |
| SCHEMBL12752441 | 0.83 | KMT2A (0.35) | KMT2AMEN1TDP1ALDH1A1KDM4E | |
| SCHEMBL12752268 | 0.83 | MEN1 (0.35) | KMT2AMEN1TDP1 | |
| SCHEMBL12752270 | 0.82 | MEN1 (0.33) | KMT2AMEN1TDP1HTT | |
| SCHEMBL12752442 | 0.82 | KDM4E (0.33) | KMT2AMEN1TDP1ALDH1A1KDM4E | |
| SCHEMBL12828760 | 0.82 | MEN1 (0.32) | KMT2AMEN1TDP1ALDH1A1KDM4E | |
| SCHEMBL12752174 | 0.82 | KMT2A (0.40) | KMT2AMEN1TDP1ALDH1A1KDM4E | |
| SCHEMBL12752207 | 0.81 | KMT2A (0.35) | KMT2AMEN1TDP1ALDH1A1KDM4E | |
| SCHEMBL12752333 | 0.81 | KMT2A (0.35) | KMT2AMEN1TDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136815-A | VIRICIDES FOR TREATMENT OF AIDS | KOREA RESEARCH INST. OF CHEM. TECH. (KR) | 2000-10-24 | — | — | US | disclosed |
| EP-0912526-A1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997043266-A1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-11-20 | — | — | WO | disclosed |