Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295755 | 0.88 | KMT2A (0.46) | KMT2AMAPK1HSD11B1 | |
| SCHEMBL2295888 | 0.88 | KMT2A (0.46) | KMT2AMAPK1HSD11B1 | |
| SCHEMBL2297334 | 0.88 | KMT2A (0.46) | KMT2AMAPK1HSD11B1GRM5ALDH1A1 | |
| SCHEMBL2296900 | 0.88 | MDM2 (0.47) | KMT2AMAPK1HSD11B1CYP3A4MDM2 | |
| SCHEMBL2295538 | 0.88 | KMT2A (0.46) | KMT2AMAPK1HSD11B1 | |
| SCHEMBL2298680 | 0.88 | KMT2A (0.46) | KMT2AMAPK1HSD11B1GRM5ALDH1A1 | |
| SCHEMBL2294941 | 0.88 | MDM2 (0.47) | KMT2AMAPK1HSD11B1CYP3A4MDM2 | |
| SCHEMBL2294266 | 0.88 | MDM2 (0.47) | KMT2AMAPK1HSD11B1CYP3A4MDM2 | |
| SCHEMBL917086 | 0.88 | MDM2 (0.47) | KMT2AMAPK1HSD11B1CYP3A4MDM2 | |
| SCHEMBL2296090 | 0.88 | KMT2A (0.46) | KMT2AMAPK1HSD11B1GRM5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009035159-A1 | 3-METHYL-2- ( (2S) -2- (4- (3-METHYL-L, 2, 4-0XADIAZ0L-5-YL) PHENYL) MORPHOLINO) -6- (PYRIMIDIN-4-YL) PYRIMIDIN-4 (3H) -ONE AS TAU PROTEIN KINASE INHIBITOR | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-19 | — | — | WO | disclosed |