Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388287 | 0.95 | CNR1 (0.45) | CNR1CNR2F10PRSS1EPHX2 | |
| SCHEMBL9199950 | 0.89 | CNR1 (0.36) | CNR1CNR2 | |
| SCHEMBL1718512 | 0.89 | NPY1R (0.42) | CNR1CNR2 | |
| SCHEMBL9202871 | 0.88 | CNR1 (0.35) | CNR1CNR2 | |
| SCHEMBL9201022 | 0.88 | CNR1 (0.41) | CNR1CNR2EPHX2 | |
| SCHEMBL1389118 | 0.88 | CNR1 (0.41) | CNR1CNR2F10PRSS1KMT2A | |
| SCHEMBL30905434 | 0.88 | CNR1 (0.41) | CNR1CNR2F10PRSS1KMT2A | |
| SCHEMBL8059066 | 0.88 | CNR1 (0.47) | CNR1CNR2KMT2A | |
| SCHEMBL8069325 | 0.88 | CNR1 (0.39) | CNR1CNR2F10PRSS1 | |
| SCHEMBL9202436 | 0.88 | CNR1 (0.34) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | claimed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | claimed |