Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069451 | 1.00 | HIF1A (0.42) | HIF1AHTTARTDP1SMN1; SMN2 | |
| SCHEMBL8079027 | 1.00 | HIF1A (0.42) | HIF1AHTTARTDP1SMN1; SMN2 | |
| SCHEMBL8077130 | 0.94 | HIF1A (0.46) | HIF1AHTTARTDP1SMN1; SMN2 | |
| SCHEMBL10870781 | 0.83 | TDP1 (0.53) | TDP1SMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL8652151 | 0.82 | TDP1 (0.41) | TDP1SMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL18287427 | 0.81 | HIF1A (0.47) | HIF1AHTTARTDP1SMN1; SMN2 | |
| SCHEMBL10629565 | 0.80 | AR (0.44) | HIF1AHTTARTDP1SMN1; SMN2 | |
| SCHEMBL10627656 | 0.78 | AR (0.46) | HIF1AHTTARTDP1SMN1; SMN2 | |
| SCHEMBL12082206 | 0.78 | HIF1A (0.54) | HIF1AHTTARTDP1SMN1; SMN2 | |
| SCHEMBL2629379 | 0.77 | HIF1A (0.49) | HIF1AHTTARTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6137008-A | USEFUL AS STARTING MATERIAL FOR MAKING FLEXIBLE AROMATIC POLYAMIDES OR POLYIMIDES | NATIONAL SCIENCE COUNCIL (TW) | 2000-10-24 | — | — | US | disclosed |