Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071540 | 1.00 | HTR2C (0.36) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL3029011 | 0.99 | HTR2C (0.36) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL3029010 | 0.99 | HTR2C (0.36) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL3027859 | 0.99 | HTR2C (0.36) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL3027852 | 0.99 | HTR2C (0.36) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL3027848 | 0.99 | HTR2C (0.36) | HTR2CHTR2AHTR2B | |
| SCHEMBL8065864 | 0.87 | HTR2C (0.37) | HTR2CHTR2AHTR2B | |
| SCHEMBL3029197 | 0.87 | HTR2C (0.37) | HTR2CHTR2AHTR2B | |
| SCHEMBL3032290 | 0.87 | HTR2C (0.37) | HTR2CHTR2AHTR2B | |
| SCHEMBL3029201 | 0.87 | HTR2C (0.37) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037220-A1 | TRICYCLIC HETEROCYCLIC DERIVATIVES | N.V. ORGANON (NL) | 2009-03-26 | — | — | WO | disclosed |