SCHEMBL8070928

SCHEMBL8070928

COc1ccccc1CCCCCCBr

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.56
SIGMAR1 Q99720 1/20 0.50
AOC3 Q16853 1/20 0.50
MPO P05164 1/20 0.49
CHRM2 P08172 8/20 0.49
GRIN1 Q05586 4/20 0.49
GRIN2A Q12879 4/20 0.49
BCHE P06276 4/20 0.49
ACHE P22303 4/20 0.49
TP53 P04637 1/20 0.49
CHRM4 P08173 1/20 0.49
CYP3A4 P08684 1/20 0.49
CHRM5 P08912 1/20 0.49
CYP2D6 P10635 1/20 0.49
CHRM1 P11229 1/20 0.49
TSHR P16473 1/20 0.49
CHRM3 P20309 1/20 0.49
THPO P40225 1/20 0.49
RECQL P46063 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663909 1.00 TAAR1 (0.56) TAAR1SIGMAR1AOC3MPOCHRM2
SCHEMBL8070776 1.00 TAAR1 (0.56) TAAR1SIGMAR1AOC3MPOCHRM2
SCHEMBL8073047 1.00 TAAR1 (0.56) TAAR1SIGMAR1AOC3MPOCHRM2
SCHEMBL8070961 1.00 TAAR1 (0.56) TAAR1SIGMAR1AOC3MPOCHRM2
SCHEMBL8072538 1.00 TAAR1 (0.56) TAAR1SIGMAR1AOC3MPOCHRM2
SCHEMBL8071154 1.00 TAAR1 (0.56) TAAR1SIGMAR1AOC3MPOCHRM2
SCHEMBL1546039 0.98 TAAR1 (0.58) TAAR1SIGMAR1AOC3MPOCHRM2
SCHEMBL79353 0.92 TAAR1 (0.60) TAAR1SIGMAR1AOC3MPOCHRM2
SCHEMBL30118964 0.92 TAAR1 (0.60) TAAR1SIGMAR1AOC3MPOCHRM2
SCHEMBL9574177 0.92 BCHE (0.56) TAAR1SIGMAR1AOC3MPOCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6063940-A Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-05-16 US disclosed
US-5637736-A Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-10 US disclosed
EP-0637580-A1 Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-02-08 EP disclosed