Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 12/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 9/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 8/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 7/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 7/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 7/20 | 0.36 |
| ▸ | PSMB11 | A5LHX3 | 6/20 | 0.36 |
| ▸ | PSMA7 | O14818 | 6/20 | 0.36 |
| ▸ | PSMA1 | P25786 | 6/20 | 0.36 |
| ▸ | PSMA2 | P25787 | 6/20 | 0.36 |
| ▸ | PSMA3 | P25788 | 6/20 | 0.36 |
| ▸ | PSMA4 | P25789 | 6/20 | 0.36 |
| ▸ | PSMA5 | P28066 | 6/20 | 0.36 |
| ▸ | PSMB4 | P28070 | 6/20 | 0.36 |
| ▸ | PSMB6 | P28072 | 6/20 | 0.36 |
| ▸ | PSMB3 | P49720 | 6/20 | 0.36 |
| ▸ | PSMA6 | P60900 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932374 | 1.00 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2PSMB8PSMB5 | |
| SCHEMBL8269958 | 1.00 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2PSMB8PSMB5 | |
| SCHEMBL20825507 | 1.00 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2PSMB8PSMB5 | |
| SCHEMBL84525 | 1.00 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2PSMB8PSMB5 | |
| SCHEMBL8082505 | 1.00 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2PSMB8PSMB5 | |
| SCHEMBL15581542 | 1.00 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2PSMB8PSMB5 | |
| SCHEMBL18257498 | 1.00 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2PSMB8PSMB5 | |
| Hydrochloric Acid SCHEMBL29079421 | 0.98 | SLC7A5 (0.45) | SLC7A5SLC1A3SLC1A2PSMB8PSMB5 | |
| Trichloroacetic Acid SCHEMBL20210932 | 0.89 | SLC7A5 (0.42) | SLC7A5SLC1A3SLC1A2PSMB8PSMB5 | |
| Trifluoroacetic Acid SCHEMBL15634857 | 0.89 | SLC7A5 (0.42) | SLC7A5SLC1A3SLC1A2PSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297678-B1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS LTD (IN) | 2021-07-07 | — | — | EP | disclosed |
| WO-2009045497-A1 | CRYSTALLINE PEPTIDE EPOXY KETONE PROTEASE INHIBITORS AND THE SYNTHESIS OF AMINO ACID KETO-EPOXIDES | PROTEOLIX, INC. (US) | 2009-04-09 | — | — | WO | disclosed |